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SPF Vision

The day where all individuals with HSP or PLS are diagnosed, treated and cured.

Welcome to SPF - (See News, Announcements & Our Address Below)

HSP and PLS are neurological disorders affecting the voluntary muscles. The disorders are progressive and may lead to patients being unable to walk, and more. The Spastic Paraplegia Foundation is dedicated to advancing research and finding the cures for two groups of closely related, progressive neurological disorders: Primary Lateral Sclerosis (PLS) and Hereditary Spastic Paraplegia (HSP).

Our process is simple, time consuming, but effective. We work with a world renowned group of scientists that are all experts in the field of neurological disorders such as HSP and PLS.  This group of scientists work with us on a volunteer basis, they live all over the world and we call them our Scientific Advisory Board (SAB). Every research proposal we receive is submitted to be reviewed, carefully analyzed and graded by at least 3 members of our SAB. Once or twice a year, our SPF Board of Directors goes to our SAB and asks them for their recommendations. The manager of our SAB, Dr. Martha Nance,  collects, compares and contrasts all of the SAB reports regarding each research proposal and turns in their report card with recommendations to our Board of Directors. We almost always follow their recommendations to support the very best HSP and PLS research in the world. The sad part of this process is that our SAB, in recent years, has graded several more of these research proposals as blue ribbon excellent than we can afford to support. Your donations are greatly needed and will be used in the most cost efficient, effective method possible.